Ligação externa

Descrição do produto

metoject® prefilled syringe / metex® prefilled syringe is a subcutaneous MTX product. It is taken once weekly and is used in the treatment of various autoimmune diseases. Key features of the product are the low injection volume, wide range of available doses, and easy application by the patient at home.

Ingrediente ativo

Methotrexat (MTX)

Modo de ação

Methotrexate is a folic acid antagonist which belongs to the class of cytotoxic agents. It acts by the competitive inhibition of the enzyme dihydrofolate reductase and thus inhibits DNA synthesis. Methotrexate is a very well-known so-called disease modifying antirheumatic drug (DMARD) meaning that it does not just relieve the pain of patients with joint inflammation and/or psoriasis, but actually helps to stop and prevent this inflammation and the resulting damage.


  • Active rheumatoid arthritis in adult patients
  • Polyarthritic forms of severe, active juvenile idiopathic arthritis, when the response to nonsteroidal anti-inflammatory drugs (NSAIDs) has been inadequate
  • Severe recalcitrant disabling psoriasis, which is not adequately responsive to other forms of therapy such as phototherapy, PUVA, and retinoids, and severe psoriatic arthritis in adult patients
  • Mild to moderate Crohn's disease either alone or in combination with corticosteroids in adult patients refractory or intolerant to thiopurines


Solução injectável:

  • 7.5 mg (0.15 ml)
  • 10 mg (0.2 ml)
  • 12.5 mg (0.25 ml)
  • 15 mg (0.3 ml)
  • 17.5 mg (0.35 ml)
  • 20 mg (0.4 ml)
  • 22.5 mg (0.45 ml)
  • 25 mg (0.5 ml)
  • 27.5 mg (0.55 ml)
  • 30 mg (0.6 ml)